Double Blind Studies have shown significant decreases in degenerative liver damage in patients with chronic liver disease
(CIRRHOSIS of the LIVER) while using Extreme Health's Liver Support Formula in as few as 30-90 days.

Recommended for those who:
Have a history of a FATTY LIVER
Consume Alcohol
Consume Tobacco Products
Have been taking Medications/Drugs
Are exposed to Environmental Toxins or Chemicals or Second Hand Smoke
Have a history of Liver or Gall Bladder Problems

Liver Support Formula (artichoke-liver-detox):
This is an extremely effective product for detoxifying the liver normalizing liver metabolism and preventing further liver damage.

The accumulation of chemicals in our body from the water that we drink and bathe in the air that we breathe and the food that we eat have been shown to weaken the immune system and contribute to the development degenerative diseases like cancer.

Liver Support System Ingredient Rationale
A proprietary blend of artichoke (Cynara Floridanum) and sarsaparilla (Smilax Aristolochiaefolia) that contains the following naturally occurring bioflavonoids and polyphenols: silymarin quercetin catechin hesperidin rutin cynarin and chlorogenic acid. Bioflavonoids are a class of water-soluble plant pigments (colors) that have anti-inflammatory antihistaminic and anti-viral properties. Health professionals formulated The Liver Support System specifically for detoxifying the liver and gall bladder and supporting each of their functions.
Included Bioflavonoids

1. Silymarin
Numerous clinical studies have shown silymarin to be among the most powerful natural agents available for the prevention and treatment of liver damage caused by exposure to human-made chemicals including alcohol induced liver degeneration and cirrhosis.

2. Quercetin
Quercetin is a bioflavonoid with antioxidant effects. It is used for the prevention of atherosclerosis hypercholesterolemia (excess cholesterol in the blood) and coronary heart disease. It can inhibit carcinogenesis and reduce capillary fragility. Quercetin is used extensively in the treatment of athletic injuries because it relieves pain and bruising and acts synergistically with Vitamin C to protect and preserve the structure of capillaries. It also promotes circulation lowers cholesterol levels and treats and prevents cataracts. Quercetin fights cancer diabetes capillary fragility and arthritis; stabilizes membranes; protects against heart disease and allergies; normalizes blood pressure; helps lowers cholesterol; and slows aging.

3. Catechin
Catechin another naturally occurring flavonoid is similar in effect to silymarin. Catechin is a powerful anti-oxidant that helps prevent free radical oxidative damage to cells. It also helps in the treatment and prevention of alcohol and chemical-induced liver disease or damage. Catechin is also valuable for its ability to neutralize intestinal toxins and assist in the stabilization of cell membranes.

4. Hesperidin
Hesperidin has been shown to be useful in clinical trials as an analgesic and anti-inflammatory.

5. Rutin
An antioxidant bioflavonoid free radical scavenger and an iron-chelator. It is used as a vascular protector for reducing capillary fragility permeability and bleeding; as a treatment for varicose vein symptoms; and as preventive for stroke (the sudden rupture or clotting/blockage of a blood vessel to the brain). Some studies show that Rutin offers protection from damage induced by asbestos the cytotoxic effects of oxidized low-density lipoproteins (LDL) and gastric injury from ethanol. It also offers some protection against DNA damage caused by hepatocarcinogens. Rutin is used extensively in the treatment of athletic injuries because it relieves pain and bruises and acts synergistically with Vitamin C to protect and preserve the structure of capillaries. It also promotes circulation lowers cholesterol levels and treats and prevents cataracts.

6. Cynarin
Cynarin assists in the detoxification of the liver and gall bladder. It also supports the function of these two important organs while and assists in their regeneration following damage. Cynarin stimulates the clearance of bile from the liver preventing congestion in the liver and thus diminishing the chances of liver damage.

7. Sarsaparilla
Sarsaparilla has been used in the treatment of the following conditions: gout arthritis digestive disorders skin diseases and cancer. Sarsaparilla contains saponins which are steroid-like agents that bind with toxins in the digestive tract. Historically sarsaparilla has been used as a 'blood purifier' and a general tonic for diseases associated with increased endotoxin levels including arthritis intestinal ulcerative conditions eczema and psoriasis.
The tonic effect of sarsaparilla is the result of its ability to stimulate the removal of accumulated waste products from the cells blood and lymph. These actions tend to increase the health of the entire body and increase vitality thereby increasing energy and endurance.

8. Chlorogenic Acid (16%)
Chlorogenic Acid is a naturally occurring water soluble phenolic acid that is a potent anti-oxidant carcinogenic inhibitor and protector against lipid peroxidation and free radical mediated cell injury.

9. Silymarin (16%)
Numerous clinical studies have shown silymarin to be among the most powerful natural agents available for the prevention and treatment of liver damage caused by exposure to human-made chemicals including alcohol induced liver degeneration and cirrhosis.

10. Quercetin
Quercetin is a bioflavonoid with antioxidant effects. It is used for the prevention of atherosclerosis hypercholesterolemia (excess cholesterol in the blood) and coronary heart disease. It can inhibit carcinogenesis and reduce capillary fragility. Quercetin is used extensively in the treatment of athletic injuries because it relieves pain and bruising and acts synergistically with Vitamin C to protect and preserve the structure of capillaries. It also promotes circulation lowers cholesterol levels and treats and prevents cataracts. Quercetin fights cancer diabetes capillary fragility and arthritis; stabilizes membranes; protects against heart disease and allergies; normalizes blood pressure; helps lowers cholesterol; and slows aging.

11. Catechin
Catechin another naturally occurring flavonoid is similar in effect to silymarin. Catechin is a powerful anti-oxidant that helps prevent free radical oxidative damage to cells. It also helps in the treatment and prevention of alcohol and chemical-induced liver disease or damage. Catechin is also valuable for its ability to neutralize intestinal toxins and assist in the stabilization of cell membranes.

12. Hesperidin
Hesperidin has been shown to be useful in clinical trials as an analgesic and anti-inflammatory.

13. Rutin
An antioxidant bioflavonoid free radical scavenger and an iron-chelator. It is used as a vascular protector for reducing capillary fragility permeability and bleeding; as a treatment for varicose vein symptoms; and as preventive for stroke (the sudden rupture or clotting/blockage of a blood vessel to the brain). Some studies show that Rutin offers protection from damage induced by asbestos the cytotoxic effects of oxidized low-density lipoproteins (LDL) and gastric injury from ethanol. It also offers some protection against DNA damage caused by hepatocarcinogens. Rutin is used extensively in the treatment of athletic injuries because it relieves pain and bruises and acts synergistically with Vitamin C to protect and preserve the structure of capillaries. It also promotes circulation lowers cholesterol levels and treats and prevents cataracts.

14. Cynarin
Cynarin assists in the detoxification of the liver and gall bladder. It also supports the function of these two important organs while and assists in their regeneration following damage. Cynarin stimulates the clearance of bile from the liver preventing congestion in the liver and thus diminishing the chances of liver damage.

15. Sarsaparilla
Sarsaparilla has been used in the treatment of the following conditions: gout arthritis digestive disorders skin diseases and cancer. Sarsaparilla contains saponins which are steroid-like agents that bind with toxins in the digestive tract. Historically sarsaparilla has been used as a 'blood purifier' and a general tonic for diseases associated with increased endotoxin levels including arthritis intestinal ulcerative conditions eczema and psoriasis.
The tonic effect of sarsaparilla is the result of its ability to stimulate the removal of accumulated waste products from the cells blood and lymph. These actions tend to increase the health of the entire body and increase vitality thereby increasing energy and endurance.

16. Chlorogenic Acid (16%)
Chlorogenic Acid is a naturally occurring water soluble phenolic acid that is a potent anti-oxidant carcinogenic inhibitor and protector against lipid peroxidation and free radical mediated cell injury.

DOUBLE BLIND STUDY
2nd Double Blind Study

COMPARATIVE STUDY BETWEEN A COMPLEX OF FLAVONOIDS AND POLYPHENOLS CREATED FROM EXTRACTS OF ARTICHOKE AND SARSAPRILLA AND A PLACEBO IN ALCOHOL RELATED LIVER DISEASE
DECEMBER 12 1998
In a previous study completed over two years ago in this same hospital an extract of artichoke (Cynara Floridanum) and sarsaparilla (Smilax Aristolochiaefolia) was evaluated in addressing the symptoms related to alcoholic liver disease. This study was accomplished over a fifteen-day period with exceptional results. Because of these results noted over a very short period of time the hospital researchers were anxious to set up the same study over a longer period (30 days). Please refer to the July 3 1996 study for descriptions of symptoms and study parameters. Results of this study are as follows:

ASCITES
A 72.38% reduction of the accumulation of serous abdominal fluid was noted in the treated group. The placebo saw a 6.35% increase in abdominal fluid.
ENCEPHALOPATHY
A 66.08% reduction of symptoms related to encephalopathy was noted in the treated group. The placebo group saw a 12.24% increase in these symptoms.
HEPATOMEGALY
The treated group experienced a 93.33% reduction in enlarged livers. In the placebo group their livers continued to enlarge by another 7.14%.
SPLENOMEGALY
An 88.40% reduction in spleen enlargement was noted with the treated group. The placebo group worsened by 11.54%.
WEAKNESS
The treated group noted a 73.64% increase in strength. There was a decrease in muscle strength by 7.41% in the placebo group.
PERIPHERAL EDEMA
Edema in the extremities of the treated patients decreased by 48.21%. There was no change in the placebo group.
HEMORRHAGES
The treated group noted a 100% decrease in capillary hemorrhaging in the skin gums and nasal membranes. The placebo group saw an increase of 28.57% in hemorrhaging.
ANOREXIA
Loss of appetite decreased in the treated group by 76.98%. The placebo group noted a decrease of 3.70%.
ABDOMINAL WALL VEINS
The treated group experienced a 60.62% decrease in tortuous veins in the abdomen related to ascites. The placebo group saw a 3.33% decrease.
PALMAR ERYTHEMA
The treated group noted a 26.67% decrease in red and swollen palms. In the placebo group there was no change.
TELANGIECTASIA
A 60.00% reduction in vascular lesions was noted in the treated group. A 3.33% reduction was seen in the placebo group.
TOTAL BILIRUBIN
The treated group noted a reduction of total bilirubin by 38.95%. The placebo group increased by 5.68%.
ALKALINE PHOSPHATASE
The treated group obtained 25.91% reduction in alkaline phosphates. There was an 11.69% increase in the placebo group.
SERUM GLUTAMIC OXALCETIC TRANSAMINASE (SGOT)
The treated group noted a decrease of 23.83% in SGOT levels. The placebo group experienced a worsening of 11.71%.
PROTHROMBIN TIME
A 42.00% reduction in clotting time was noted with the treated group. An increase in clotting time was noted in the placebo group of 6.60%.
SERUM ALBUMIN
An increase of 37.27% in serum albumin was noted in the treated group. There was a decrease in the placebo group of 1.95%.
GAMMA GLUTAMYL TRANSPEPTIDASE (GGT)
The treated group noted a reduction of 23.79% in GGT. The placebo group experienced an increase of 9.92%.
DR. CHARLES COCHRAN

1st Double Blind Study
INTERPRETATION OF RESULTS OBTAINED IN A DOUBLE BLIND TEST MADE IN THE GENERAL HOSPITAL MEXICO WITH THE PRODUCT LIVER SUPPORT ON PATIENTS HAVING CHRONIC ALCOHOLIC HEPATIC DISEASE.
In order to analyze carefully the results of this study it is necessary to know the importance of the two clinical and laboratory parameters intervening in the calculations of Orrego and Maddrey Indexes. We will compare the results of the parameters the placebo control and the Liver Support groups on both indexes. The results are presented as percentages of recovery and are obtained from the data obtained from each group of 30 patients; we will get an average of those results at the beginning and at the end of the study. Both averages will give us a final recovery compared to the initial values. This way we may demonstrate the effectiveness of Liver Support
DEFINTIONS AND RESULTS OF PARAMETERS
ASCITES- Effusion and accumulation of serous fluid in the abdominal cavity. The experimental group (Liver Support) experienced a 28.8% reduction of ascites while the placebo group experienced no change.
ENCEPHALOPATHY- a DEGENERATIVE DISEASE OF THE BRAIN. Hepatic encephalopathy- a condition usually occurring secondarily to advanced disease of the liver. It is marked by disturbances of consciousness that may progress to deep coma (hepatic coma) psychiatric changes of varying degree
flapping tremor and fetor hepaticas. Also called portal-systemic encephalopathy. Patients on Liver Support experienced a 34.55% reduction of hepatic encephalopathy. The placebo group experienced a 5.5% reduction.
SPLENOMEGALIA- Enlargement of the spleen. An 18.18% reduction was observed in the Liver Support group and a 55% reduction was observed in the placebo group.
WEAKNESS- Lacking physical strength or vigor marked by asthenia atony cardiasthena enervation fatigue and lassitude. The Liver Support group experienced an 83.45% decrease in the incidence of weakness while the placebo group reported no change.
PERIPHERAL EDEMA- A condition in which the body tissues contain an excess amount of fluid. The Liver Support Group experienced an 11.10% reduction in peripheral edema while the placebo group had a 0.69% reduction.
HEMORRHAGES- Bleeding. This was one of the most important benefits observed in the Liver Support group. The Liver Support group had an 89.41% reduction in hemorrhages while the placebo had a 31% reduction.
ANOREXIA- Loss of appetite. Seen in depression malaise commencement of fevers and illness also in disorders of the alimentary tract especially of the stomach and as a result of alcoholic excess and drug addiction. Anorexia was diminished by 86.07% in the Liver Support group. There was no change in the placebo group.
TOTAL BILIRUBIN LEVEL - The predominant pigment of human bile. Total serum bilirubin may be increased in cirrhosis of the liver and acute viral hepatitis. The Liver Support group obtained 25.11% reduction in bilirubin whereas the placebo group had a 7.2% increase.
OGT - (Oxalacetic Glutamic Transaminase). It is distributed all over body tissue especially in the heart and liver. Less amounts are found in the spleen pancreas kidneys lungs and brain. Any lesion of a tissue leads to the secretion of this enzyme to the blood stream. The activity of OGT is risen under hepatic necrosis cirrhosis of the liver or hepatic metastasis. In those patients who received Liver Support this level diminished 22.56% in only 15 days of treatment and in the placebo group it diminished 8.51%.
PROTHROMBINE TIME - A test of clotting time made by determining the time for clotting to occur after thromboplastin and calcium are added to decalcified plasma. There was 30.82% reduction in prothrombin time for Liver Support patients whereas the placebo group's time increased 1.25%. This is very important data because it means that Liver Support helps the healing of wounds faster.
SERUM ALBUMIN - One of a group of simple proteins widely distributed in tissues. Albumin is a constituent of blood. Low levels of albumin in blood plasma are associated with a pathologic condition of the liver. The Liver Support group experienced an increase of 8.85% of total albumin levels while the placebo group experienced a 5.35% increase.

AUTISM AND DETOXIFICATION
Might autistic children be the proverbial "canaries in the coal mine" whose nervous systems are more susceptible to the impact of toxic heavy metals in the environment incurring neurological damage even at low exposure levels? One recent study found that in one group of 18 autistic children 16 had blood levels of toxic heavy metals and chemicals exceeding adult maximum tolerance. This build-up of toxins may not arise simply from excessive exposure but from a marked inability to process and eliminate toxins from the body. Indeed when the children were assessed using a biochemical analysis to gauge the body's ability to detoxify substances researchers found that every child showed out-of-range results suggesting a defect in this two-phase detoxification process. Researchers explained that such a mechanism could lead to a backup of toxic heavy metals and chemical toxins with increased free radical activity in the body. Since the blood-brain barrier of children is still not fully developed these toxic and oxidized molecules could penetrate into regions of the brain and damage neutrons receptors synapses enzymes and cell mitochondria and also set off auto immune reactions triggering further damage.

According to other studies autistic children may have problems metabolizing and detoxifying certain compounds due to an impaired biochemical process called sulfation. Sulfation plays an important role in the second phase of the detoxification process. Impaired sulfation could make autistic children more vulnerable to multiple heavy metal and chemical sensitivities. It may also help explain an exacerbation of behavioral problems after children eat foods containing phenol tyramine and phenyl compounds which are normally neutralized through the sulfation process.

Much concern has been raised over the link between exposure to heavy metal toxins and neurological brain damage associated with learning and behavior disorders in children. Indeed research shows that exposure to heavy metals such as lead mercury and antimony can impair brain development at very early ages even at low doses previously deemed "harmless." Children are particularly susceptible to the deleterious effects of heavy metal exposure for several reasons. First their developing nervous systems are more sensitive. Second their bodies absorb toxins more rapidly yet clear them from the system more slowly than from adults. Finally a child's blood-brain barrier the natural protective mechanism which blocks harmful substances from entering and damaging the brain is not yet fully formed.

Many professionals working in the field of autism have expressed concern that some autistic children were exposed to potentially damaging levels of ethylmercury which is a preservative used in certain vaccinations. Clinical neurobehavioral symptoms of mercury poisoning seem to parallel closely many common symptoms of autism. In response to pressure from the FDA the U.S. Public Health Service and other regulatory health agencies vaccine manufacturers have since worked to reduce or eliminate the use of ethylmercury as a preservative in many vaccines.

In addition several studies have associated high lead levels in children with autism. Elevated levels of lead in hair - signify long-term toxic exposure to this heavy metal - were correlated with increased behavior abnormalities and learning disorders in children. Based on clinicians' observations antimony a potential toxin found in some fire retardant materials is also a possible cause for concern.

Nutritional balance and healthy metabolism are also very important. Dr. Lynn Wecker and his colleagues at Louisiana State Medical Centre observe that trace element imbalances in the human body can disrupt neurotransmitter function and produce marked changes in behavior; many of which are consistent with symptoms of autism. For this reason Dr. Wecker and his team evaluated trace element concentrations in the hair of autistic children. They found clear deficiencies of calcium copper zinc and chromium that were so striking that they allowed them to discriminate between autistic children and healthy controls with a high degree of accuracy using just test results. Deficiencies of mineral nutrients can make a child more susceptible to heavy metal absorption. Magnesium deficiencies associated with attention-deficit disorder and hyperactivity may also be clinically significant in autism. Extreme Health's Liver Support Formula radically improves liver metabolism and promotes the detoxification of the liver and the body.

Buy Now

REFERENCES:
Accardo P Whitman B Caul J Rolfe U. Autism and plumbism. A possible association. Clinical Pediatric 1988; 27(1):41-4. Alberti A Pirrone P Elia M Waring RH Romano C. Sulphation deficit in "low-functioning" autistic children: a pilot study. Biol Psychiatry 1999;46(3):420-4. Cohen DJ Johnson WT Caparulo BK. Pica and elevated blood lead level in autistic and atypical children. Am J Dis Child 1976;130(1):47-48. Edelson SB Cantor DS. Autism: Xenobiotic influences. Toxicology and industrial health 1998;14(4):553-563. Emory E Pattillo D Archibald E Byroh M Sung F. Neurobehavioral effects of low-level lead exposure in human neonates. Am J Obstet Gynecol 1999;181:S2-S11. Eufemia P Celli M Finocchiaro R Pacifico L Viozzi L Zaccagnini M Cardi E Giardini O. Abnormal intestinal permeability in children with autism. Acta Paediatr 1996:85(9):1076-9.
Goodwin MS Cowen MA Goodwin TC. Malabsorption and cerebral dysfunction: a multivariate and comparative study of autistic children. J Autism Child Schizophr 1971; 1:48-62. Halsey NA. Limiting infant exposure to thimerosal in vaccines and other sources of mercury. JAMA. 199 Nov 10;282(18):1763-6. Horvath K Papadimitriou JC Rabsztyn A Drachenberg C Tildon JT. Gastrointestinal abnormalities in children with autistic disorder. J. Pediatr 1999; 135:559-63. Kozielec T Starobrat-Hermelin B. Assessment of magnesium levels in children with attention deficit hyperactivity disorder (ADHD). Magnes Res; 1997 Jun; 10(2):143-8. Lanphear BP Dietrich K Auinger P Cox C. Subclinical lead toxicity in U.S. children and adolescents [abstract#894]. APS/SPR Joint Meeting; 2000 May 12-16; Boston MA. McFadden SA. Phenotypic variation in xenobiotic metabolism and adverse environmental response: focus on sulfur-dependent detoxification pathways. Toxicology 1996;111 (1-3):43-65. Shannon M Graef Jw. Lead intoxication in children with pervasive developmental disorders. J Toxicol Clin Toxicol 1996;34(2):177-81. Tuthill RW. Hair lead levels related to children's classroom attention-deficit behavior. Arch Enciron Health 1996;(3):214-220. Wecker L Miller SB Cochran SR Dugger DL Johnson WD. Trace element concentrations in hair from autistic children. J Ment Defic Res 1985; 15-22. Wilson MA Johnston MV Goldstein GW Blue ME. Neonatal lead exposure impairs development of rodent barrel field cortex. PNAS 2000; 97(10):5540-5545.

Read more information on

HEPATITIS LIVER CIRRHOSIS/HCC
Increasing Evidence Suggest Extreme Health's Liver Support Formula may be Effective in Compromising the Detrimental Effects of Hepatitis-Engendered Cirrhosis

A Decrease in Cirrhosis of the Liver
Author: Dr. Charles Cochran

Back to the top of the page